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Gabapentin elimination half-life is 5 to 7 hours and is unaltered by dose or following multiple dosingGabapentin elimination rate constantplasma clearanceand renal clearance are directly proportional to creatinine clearanceIn elderly patientsand in patients with impaired renal functiongabapentin plasma clearance is reducedGabapentin can be removed from plasma by hemodialysis.

Use only the brand and form of gabapentin your doctor has prescribedCheck your medicine each time you get a refill to make sure you receive the correct form.

Pharmacokinetic differences due to race have not been studiedBecause gabapentin is primarily renally excreted and there are no important racial differences in creatinine clearancepharmacokinetic differences due to race are not expected.

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